4moms was a Pittsburgh-based baby products company known for innovative products including the mamaRoo infant swing. UPPAbaby acquired 4moms through an asset purchase agreement in July 2024, integrating the brand and its products under the UPPAbaby umbrella.

AlgenAir is a company that develops living air purification technology using microalgae. Its flagship product, the aerium, is a natural indoor air purifier that uses Spirulina to produce oxygen and reduce carbon dioxide, providing the photosynthetic benefit equivalent to over 25 plants.

Allpoint Systems, LLC is a software and data processing company that offers solutions for collecting and processing LiDAR (laser) data. The company serves customers who work with geospatial and point-cloud datasets.

BAM! is a startup that provides a battery-powered heating solution enabling users to enjoy perfectly heated meals anywhere. The company was selected as part of AlphaLab's first combined cohort, announced in February 2025.

Bansen Labs is a Pittsburgh-based startup making consumer technology more accessible for people with disabilities. The company has received an NSF Phase I SBIR grant and won the Social Enterprise Category and the 2016 Louisiana Startup Prize.

Bindr is a Pittsburgh-based LGBTQ and bisexual dating app designed as a label-free, inclusive platform where users connect based on who they are rather than sexual orientation. The company won the 2SLGBTQIA+ Entrepreneur Prize sponsored by QueerTech and a $60k prize from Technically.

Buoy Hydration makes liquid electrolyte drops that transform any drink into a hydrating, functional beverage with trace minerals and no sugar. The company offers clean hydration supplements and immune support products designed for everyday wellness.

Chela is a multi-brand marketplace platform connecting consumers with curated, edgy, and unique emerging sustainable fashion designers from around the world. Founded in 2020, the company has raised $50K and operates as Chela System Inc.

DashStrom is a Pittsburgh-based education startup that runs out-of-school programs combining active games with social-emotional learning to help children build confidence, grit, and a growth mindset. The company was named a 2026 Startup to Watch and is backed by InnovationWorks.

Day Owl is a sustainable backpack company that makes essential everyday carry products from ethically recycled plastic. Bags are extra durable, individually numbered, and backed by free shipping, free returns, and a free end-of-life recycling program.

Diamond Kinetics is a Pittsburgh-based sports technology company that uses sensor technology and motion analytics to help baseball and softball players improve their batting mechanics and overall performance. The company offers a bat sensor and companion mobile app, and was developed in partnership with the University of Pittsburgh.

EKTO VR is a technology company developing immersion-enhancing products for virtual reality users, starting with a compact wearable robotic footwear system designed to mitigate motion sickness and deepen immersion. The company aims to fulfill the sci-fi promise of virtual reality through revolutionary hardware products.

EXG Wear is a Pittsburgh-based health and wellness technology company developing a compact earbud sensor that generates actionable commands from brain wave signals, eye movements, and facial gestures. The device is designed to augment human wellness and productivity in everyday life. The company is a portfolio company of Innovation Works.

Foxblossom Co. is a Pittsburgh, Pennsylvania-based gifting company offering luxury curated gifts, custom gift design, packaging design, private label products, swag kits, and on-demand fulfillment. The company serves both individual consumers via a Build a Box app and corporate clients.

FutureDerm, Inc. was a skincare company focused on science-backed beauty products, subsequently acquired by Columbia Skincare, a medical-grade microbiome-friendly skincare brand based in the US.

Honeycomb Credit is an investment crowdfunding platform that connects growing small and medium-sized brick-and-mortar businesses with local everyday investors. The platform enables local businesses to raise growth capital from their communities, building financially empowered Main Streets. One business on the platform raised $213,000 through investment crowdfunding.

ModCloth, Inc. is an American online retailer of indie and vintage-inspired women's clothing, headquartered in Los Angeles, California. The company offers unique styles and original prints reimagining women's fashion, and is owned by Nogin, Inc.

Module is a Pittsburgh, Pennsylvania-based high-tech housing startup that designs, manufactures, and builds small, ultra-energy-efficient homes that snap together from prefabricated parts. The company focuses on sustainable housing solutions through innovative design and modular construction processes for modern living.

Naima Health is a digital health company that develops tools using behavioral decision science, clinical science, and machine learning to engage patients in their clinical care. The company's platform is designed to help patients more actively participate in managing their own health outcomes.